1st Closed Editorial Board Meeting of TG Forum
Keynote – Remnant cholesterol
Prof Børge Nordestgaard presented data from the Copenhagen General Population Study showing that, although the remnant fraction (VLDL and TRLs) typically transports less cholesterol than the LDL fraction of plasma (25 mg/dL [0.6 mmol/L] vs 115 mg/dL [3 mmol/L]), nonetheless these two fractions of plasma cholesterol are associated with comparable increased MI risk.
Watch presentation >
Keynote – Atherogenic potential of postprandial lipaemia in diabetes
Prof Marja-Riitta Taskinen demonstrates that there are multiple disturbances in TRL metabolism in patients with type 2 diabetes (T2D), resulting in excess generation of remnant particles from both intestine and liver derived TRLs with long residence times in the circulation. As apoC-III is raised in T2D, could it be a promising therapeutic target?
Watch presentation >
Clinical trials of innovative therapeutics
New insights into the biology of triglyceride metabolism underpin the development of novel therapies for managing hypertriglyceridaemia to reduce the risk of atherosclerotic cardiovascular disease (ASCVD) and, for severely elevated levels, pancreatitis.
In the last decade epidemiology and genetic studies – in particular, Mendelian randomisation studies – have moved the field forward and we are on the cusp of a new era in managing elevated triglycerides. Major outcomes studies with these new therapies are fundamental to answering the much-debated question:
Does lowering elevated triglycerides reduce residual cardiovascular risk?
About Triglyceride Forum
The Triglyceride Forum is a unique, independent, expert-led global initiative to address the rapidly evolving field of triglycerides and triglyceride-rich lipoproteins in cardiovascular disease and pancreatitis. This Forum will provide clinicians and researchers with international, open access, peer-reviewed resources at an important time when new and innovative molecules are at advanced stages of development… Read more >>
Professors Ginsberg and Chapman explain the fundamental scientific and clinical research that has turned the spotlight on triglyceride-rich lipoproteins and their remnants as important players in the development of atherosclerotic CVD and pancreatitis and as targets for novel therapies for both these serious diseases.
Join the Triglyceride Forum for open access to independent, evidence based knowledge and high quality educational programmes
View invitation from Henry Ginsberg
Join the Triglyceride Forum to share new data and exchange opinions with clinicians and researchers around the world
View invitation from John Chapman
MAKING THE CONNECTION: TRIGLYCERIDES, RESIDUAL CV RISK AND PANCREATITIS
This unique, downloadable slide deck developed specially for Triglyceride Forum is a state-of-the-art guide to triglycerides and their association with residual cardiovascular risk and pancreatitis.