The ANGPTL3 siRNA, AZD1705, has demonstrated a favourable safety profile and dose dependent reductions in ANGPTL3, TG, LDL-C, apoB and non-HDL-C in a Phase 1 single and multiple ascending dose study in patients with mixed dyslipidaemia.
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Financial support was provided as a GMG Knowledge Gap Grant from Pfizer Inc.
Financial support was provided as a GMG Knowledge Gap Grant from Pfizer Inc.
Financial support was provided as a GMG Knowledge Gap Grant from Pfizer Inc.